T2-weighted MRI, Canavan disease

Spongy degeneration of cerebral white matter (Canavan disease). Magnetic resonance imaging study. T2-weighted axial views show a marked increase in signal in the white matter that is most evident in the posterior portions of the hemispheres.

MRI: magnetic resonance imaging.

Courtesy of Dr. Franklin G Moser, Division of Neuroradiology, Cedars-Sinai Medical Center, Los Angeles, CA. Reproduced from: Menkes JH. Heredodegenerative Diseases. In: Child Neurology, 6th Edition, Menkes JH, Sarnat HB, Maria BL (Eds), Philadelphia, Lippincott Williams & Wilkins, 2006.

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T2-weighted MRI, Canavan disease