Egg content of vaccines (subject to change - check package inserts)

Vaccine	Grown in	Egg protein content	Approach in egg-allergic patient
Measles and mumps	Chick embryo fibroblast cell cultures	Picograms to nanograms	Administer in usual manner
Purified chick embryo rabies	Chick embryo fibroblast cell cultures	Picograms to nanograms	Administer in usual manner
Influenza (killed injected and live attenuated nasal)	Chick extra-embryonic allantoic fluid	<1 microgram	*
Yellow fever	Chick embryos	Micrograms	Skin test with vaccine prior to administration

* Discussed in the UpToDate topic on influenza vaccination in individuals with egg allergy.

Graphic 51011 Version 4.0

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