Version June 2024
| Atopic dermatitis |
| Flexural areas, face, eyelids, and hands frequently involved |
| Personal or family history of flexural eczema, asthma, allergic rhinitis, or hay fever during infancy or childhood |
| Irritant contact dermatitis |
| History of irritant exposure |
| More demarcated and less itchy than allergic contact dermatitis |
| Patch testing usually negative; may coexist with allergic contact dermatitis |
| Seborrheic dermatitis |
| Greasy, scaly plaques in the central part of the face |
| Frequent involvement of scalp, eyebrows, and eyelids |
| Central chest and folds sometimes involved |
| Absence of edema and vesiculation |
| Dyshidrotic eczema |
| Recurrent vesicular eczema of the hands and/or feet |
| Deep-seated, multilocular vesicles on the sides of the digits and on palmar or plantar skin |
| Dorsal surfaces usually not involved |
| Psoriasis |
| Demarcated, erythematous, and scaly plaques; frequent involvement of elbows and knees; nail pitting may be seen at close inspection |
| Absence of vesiculation, but pustules may be present on palms and soles |
| When limited to palms and soles, may be difficult to distinguish from chronic allergic contact dermatitis |
| Stasis dermatitis |
| Medial aspects of lower legs usually involved; skin color changes are frequent |
| Other signs of chronic venous insufficiency usually present |
| Persistent stasis dermatitis suggests secondary contact sensitization |
| Asteatotic eczema (eczema craquelé) |
| Crackled patches of dry skin on the lower legs |
| Lack of inflammation |
| Tinea manuum |
| Typically unilateral and asymmetrical |
| Inflammatory edge |
| Sometimes associated with an autoeczematization reaction |
| Autoeczematization (autosensitization) reaction |
| Diffuse, pruritic, papulovesicular eruption |
| May be associated with allergic contact dermatitis, stasis dermatitis, and bacterial or fungal infection |
| Mycosis fungoides (patch and plaque stage) |
| Scaly patches or plaques, often pruritic, most frequently located on the trunk |
| History of lesions waxing and waning over years |
| Absence of edema and vesiculation |
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