Manifestations of primary biliary cholangitis

Manifestations of PBC

Fatigue

Pruritus

Portal hypertension

Metabolic bone disease

Xanthomas

Fat-soluble vitamin malabsorption

Urinary tract infection

Malignancy

Associated disorders

Thyroid dysfunction

Sicca syndrome

Limited cutaneous systemic sclerosis or scleroderma overlap syndromes

Raynaud phenomenon

Rheumatoid arthritis

Celiac disease

Inflammatory bowel disease

PBC: primary biliary cholangitis.

Adapted from: Heathcote EJ. Management of primary biliary cirrhosis. The American Association for the Study of Liver Diseases practice guidelines. Hepatology 2000; 31:1005.

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