Version June 2024
| Condition | Location of pain or discomfort | Character of discomfort | Onset relative to exercise | Effect of rest | Effect of body position | Other features |
| Intermittent claudication | Buttock, thigh, or calf muscles and rarely the foot | Cramping, aching, fatigue, weakness, or pain | After some degree of exercise | Quickly relieved | None | Reproducible |
| Nerve root compression (eg, herniated disc) | Radiates down leg, usually posteriorly | Sharp lancinating pain | Soon after, if not immediately after onset | Not quickly relieved. (Also, often present at rest) | Adjusting back position may relieve pain | History of back problems |
| Spinal stenosis | Hip, thigh, or buttock (within affected dermatome) | Motor weakness more prominent than pain | After walking or standing for some length of time | Relieved by resting only if position changed | Relieved by lumbar spine flexion (sitting or stooping forward) | Frequent history of back problems, provoked by intraabdominal pressure |
| Hip arthritis | Hip, thigh, buttocks | Aching discomfort, usually localized to hip and gluteal region | After variable degree of exercise | Not quickly relieved (and may be present at rest) | More comfortable sitting (ie, weight taken off legs) | Variable, may relate to activity level, weather changes |
| Arthritic, inflammatory processes | Foot, arch | Aching pain | After variable degree of exercise | Not quickly relieved (and may be present at rest) | May be relieved by not bearing weight | Variable, may relate to activity level |
| Venous claudication | Entire leg, but usually worse in thigh and groin | Tight, bursting pain | After walking | Subsides slowly | Relief speeded by elevation of the extremity | History of iliofemoral deep vein thrombosis, signs of venous congestion, edema |
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