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A safety checklist for using HFNO for apneic oxygenation during laryngotracheal surgery

A safety checklist for using HFNO for apneic oxygenation during laryngotracheal surgery
Pre-procedure
  1. Before surgery, establish patient suitability for this technique
  1. At the multidisciplinary team brief, confirm each patient's suitability, agree on an individualized immediately deliverable rescue oxygenation strategy and the SpO2 value that triggers intervention
  1. Undertake the entire procedure in the operating room. Prior to induction, complete the WHO Surgical Safety Checklist (adapted as necessary).
  1. Apply standard monitoring and note baseline SpO2 prior to commencement of HFNO
  1. Check gas is flowing through nasal cannulae and ensure the humidifier is at the chosen temperature
  1. Position the patient in a head-up position. Optimize operating room ergonomics.
  1. Commence HFNO (FiO2 1.0), increasing gas flow to ≥50 liters minute–1, as tolerated (≥5 minutes of preoxygenation, ideally with mouth closed)
  1. Check SpO2 has risen above baseline (ideally to 100%). If the desired SpO2 is not achieved, consider suitability of this technique.
  1. Apply remaining monitoring, including carbon dioxide monitoring (if available)
  1. At the surgical pause, ensure entire team readiness (including clear role allocation) and that the patient is draped prior to induction of anesthesia
  1. Ensure the equipment for the patient's individualized rescue oxygenation strategy is immediately available and functional (eg, facemask, supraglottic airway, laryngoscope, microlaryngoscopy tube, or jet ventilation kit)
Peri-procedure
  1. Administer total intravenous anesthesia. Rocuronium is recommended if a neuromuscular blocking drug is used. Ensure the oxygen gas flow is set at 70 liters minute–1.
  1. Maintain airway patency with jaw thrust +/– oropharyngeal airway until surgical instrumentation
  1. Check effectiveness of facemask ventilation prior to commencing surgery (with waveform capnography)
For compressible nasal cannulae with flow-diversion capability (eg, Optiflow Switch), this is achieved without removal of cannulae
  1. Commence surgery, ensuring a patent airway is maintained throughout
Post-procedure
  1. Be ready to retake control of the airway on procedure completion (this can be achieved by jaw thrust +/– airway adjunct with continued HFNO, face mask, supraglottic airway or tracheal intubation)
  1. Prior to emergence, reverse neuromuscular blocking drug if used (if rocuronium is used, then sugammadex is recommended)
  1. Confirm adequate spontaneous respiration before transfer to the post anesthesia care unit
  1. Consider taking HFNO nasal cannulae to post anesthesia care unit with patient to facilitate ongoing HFNO, as required.
This table provides a checklist for safe and effective use of HFNO during laryngotracheal surgery. It was developed by an international group of experts in the use of HFNO in this setting.
HFNO: high flow nasal oxygen.
Reproduced with permission from Wolters Kluwer Health, Inc.: Ghosh P, Ward PA, Orrock JL, et al. A safety checklist for apnoeic oxygenation using high-flow nasal oxygen for laryngotracheal surgery in adults: An international Delphi consensus. Eur J Anaesthesiol 2025; 42(4):357-365. Copyright © 2025 European Society of Anaesthesiology and Intensive Care. https://journals.lww.com/ejanaesthesiology/pages/default.aspx.
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