Fasting plasma glucose |
Falsely low - Delayed processing
- Improper collection (eg, use of tube that does not inhibit glycolysis)
- Improper handling (eg, lack of refrigeration)
- Inadequate fasting
- Acute stressors, including physical illness
- Acute, intense exercise (within 1 hour of collection)
- Medications (eg, glucocorticoids)
|
Glycated hemoglobin (A1C) |
Falsely low (high RBC turnover) - Chronic hemolysis (thalassemia, G6PD deficiency)
- Treatment for iron, vitamin B12, or folate deficiency
- Erythropoietin treatment
- Hemodialysis
- Advanced chronic kidney disease (eGFR <30 mL/min/1.73 m2)
- Acute blood loss
- Blood transfusion
- HIV infection
- Iron deficiency anemia
- Vitamin B12 or folate deficiency anemia
|