In this patient, loop ileostomy closure was complicated by deep surgical site infection and fascial dehiscence, which was managed with placement of Vicryl mesh with new loop ileostomy creation. He developed multiple (3) small bowel EAFs with no evidence of distal bowel obstruction. After transfer, we managed with NPWT with incremental delayed primary skin closure, then elevation of suprafascial skin and subcutaneous tissue flaps and drain placement, medical management with antimotility and antisecretory medications, PN, and he fully healed and is tolerating a regular diet.