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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : -79 مورد

ILAR classification criteria for JIA in patients under 16 years

ILAR classification criteria for JIA in patients under 16 years
Subtype of JIA Duration of symptoms Inclusion criteria Exclusion criteria
Systemic arthritis (systemic JIA) ≥2 weeks Arthritis in ≥1 joint and fever (with at least 3 days of a quotidian pattern), plus ≥1 of the following features:
  • Evanescent erythematous rash
  • Generalized lymphadenopathy
  • Hepatomegaly and/or splenomegaly
  • Serositis
  • A personal history of or first-degree relative affected by psoriasis
  • A personal history of or first-degree relative affected by certain conditions (including ERA, ankylosing spondylitis, sacroiliitis with IBD, reactive arthritis, and/or acute anterior uveitis)
  • Arthritis starting after 6 years of age in a male patient who is positive for HLA-B27
  • Positive testing for RF*
Oligoarticular arthritis (oligoarticular JIA) ≥6 weeks

Arthritis affecting 1 to 4 joints during the first 6 months of disease

Considered persistent oligoarticular JIA if patients continue to have arthritis in 1 to 4 joints, versus extended oligoarticular JIA if patients go on to develop arthritis in ≥4 joints
  • A personal history of or first-degree relative affected by psoriasis
  • A personal history of or first-degree relative affected by certain conditions (including ERA, ankylosing spondylitis, sacroiliitis with IBD, reactive arthritis, and/or acute anterior uveitis)
  • Arthritis starting after 6 years of age in a male patient who is positive for HLA-B27
  • Positive testing for RF*
  • Features consistent with systemic JIA
Polyarticular arthritis (polyarticular JIA) ≥6 weeks

Arthritis affecting ≥5 joints affected during the first 6 months of disease

Further categorized as being positive or negative for RF*
  • A personal history of or first-degree relative affected by psoriasis
  • A personal history of or first-degree relative affected by certain conditions (including ERA, ankylosing spondylitis, sacroiliitis with IBD, reactive arthritis, and/or acute anterior uveitis)
  • Arthritis starting after 6 years of age in a male patient who is positive for HLA-B27
  • Features consistent with systemic JIA
Psoriatic arthritis (psoriatic JIA) ≥6 weeks Simultaneous arthritis and psoriasis or arthritis plus ≥2 of the following:
  • Dactylitis
  • Nail pitting or onycholysis
  • Psoriasis in a first-degree relative
  • A personal history of or first-degree relative affected by certain conditions (including ERA, ankylosing spondylitis, sacroiliitis with IBD, reactive arthritis, and/or acute anterior uveitis)
  • Arthritis starting after 6 years of age in a male patient who is positive for HLA-B27
  • Positive testing for RF*
  • Features consistent with systemic JIA
Enthesitis-related arthritis (ERA) ≥6 weeks Arthritis and enthesitis, or arthritis or enthesitis plus ≥2 of the following:
  • The presence of or history of sacroiliac joint tenderness and/or inflammatory back pain
  • HLA-B27 positivity
  • Onset of arthritis in a male over 6 years of age
  • Acute anterior uveitis
  • History in a first-degree relative of ankylosing spondylitis, ERA, sacroiliitis with IBD, reactive arthritis, or acute anterior uveitis
  • A personal history of or first-degree relative affected by psoriasis
  • Positive testing for RF*
  • Features consistent with systemic JIA
Undifferentiated arthritis ≥6 weeks Patient does not meet the above criteria or if they fulfill criteria for 2 or more categories  
To be used with UpToDate content on classification of JIA.

HLA: human leukocyte antigen; IBD: inflammatory bowel disease; ILAR: International League of Associations for Rheumatology; JIA: juvenile idiopathic arthritis; RF: rheumatoid factor.

* Positive testing for RF is defined as having a positive immunoglobulin M RF test on at least 2 occasions checked at least 3 months apart within the first 6 months of disease.

¶ Examples include fever, evanescent rash, and elevated ferritin.
Adapted from: Petty RE, Southwood TR, Manners P, et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: Second revision, Edmonton, 2001. J Rheumatol 2004; 31:390.
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