Screening for and management of vitamin D deficiency in nonpregnant adults

This algorithm illustrates our approach to screening for and managing vitamin D deficiency in adults. Practice varies, and other experts may reasonably use a different approach.

25(OH)D: 25-hydroxyvitamin D; RDA: Recommended Dietary Allowance.

* When available, we prefer cholecalciferol (vitamin D3) rather than ergocalciferol (vitamin D2). Trial data suggest faster normalization of vitamin D levels with vitamin D3 over that seen with vitamin D2; however, the magnitude of this effect is likely not clinically significant for most patients.

¶ Patients with severe vitamin D deficiency are at risk for developing osteomalacia. In such patients, we measure:

Serum calcium, phosphorus, alkaline phosphatase, parathyroid hormone (PTH)
Electrolytes, blood urea nitrogen (BUN), creatinine
Tissue transglutaminase antibodies (to assess for celiac disease)

Graphic 141712 Version 2.0

خرید پکیج

Screening for and management of vitamin D deficiency in nonpregnant adults