Macroscopic and microscopic appearance of adenomyosis

Thickened and trabeculated appearing myometrial wall with ill-defined hypertrophic swirls of smooth muscle of sectioned uterus with adenomyosis (A, inset). Histopathological image of uterine adenomyosis observed in hysterectomy specimen, with endometrial glandular and stroma invading the muscular myometrium (within circle) (A). Higher-power view showing ectopic endometrial glands and stroma surrounded by hyperplastic myometrium (asterisk) (B). Ectopic glandular epithelium is proliferative type and stroma is inactive, non-mitotic and composed of monotonous cells (B). Hematoxylin and eosin stain.