Suggested epinephrine dosing in children if a 0.1 mg autoinjector IS available

	Manufacturer weight range^[1]	Suggested weight range to account for lack of ideal doses^[2]
0.1 mg autoinjector	7.5 to <15 kg (16.5 to <33 lbs)	7.5 to <13 kg (16.5 to <28.6 lbs)
0.15 mg autoinjector	15 to <30 kg (33 to <66 lbs)	13 kg to <25 kg (28.6 to <55 lbs)
0.3 mg autoinjector	≥30 kg (≥66 lbs)	≥25 kg (≥55 lbs)

The suggested weight range addresses lack of precision in dosing with autoinjectors and is based on expert opinion and risk and benefit of selecting a fixed dose based on patient weight.^[2] Dosing decisions should be individualized according to patient characteristics and caretaker preferences (eg, severity of allergy, comorbid conditions).

References:

Epinephrine injection. United States Prescribing Information. Revised September 2019. US National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6180fb40-7fca-4602-b3da-ce62b8cd2470 (Accessed on October 4, 2022).
American Academy of Pediatrics. Allergy and Anaphylaxis Emergency Plan. https://downloads.aap.org/HC/AAP_Allergy_and_Anaphylaxis_Emergency_Plan.pdf (Accessed on October 4, 2022).

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Suggested epinephrine dosing in children if a 0.1 mg autoinjector IS available