Suggested epinephrine dosing in children if a 0.1 mg autoinjector is NOT available

	Manufacturer weight range^[1]	Suggested weight range to account for lack of ideal doses^[2]
0.15 mg autoinjector	15 to 30 kg (33 to 66 lbs)	7.5 to <25 kg (16.5 to <55 lbs)
0.3 mg autoinjector	≥30 kg (≥66 lbs)	≥25 kg (≥55 lbs)

The suggested weight range addresses lack of precision in dosing with autoinjectors and is based on expert opinion and risk and benefit of selecting a fixed dose based on patient weight.^[2] Dosing decisions should be individualized according to patient characteristics and caretaker preferences (eg, severity of allergy, comorbid conditions).

References:

Epinephrine injection. United States Prescribing Information. Revised December 29, 2020. US National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7560c201-9246-487c-a13b-6295db04274a (Accessed on October 4, 2022).
Sicherer SH, Simons FER, Section on Allergy and Immunology. Epinephrine for first-aid management of anaphylaxis. Pediatrics 2017; 139:e20164006.

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Suggested epinephrine dosing in children if a 0.1 mg autoinjector is NOT available