Neurologic disorders that affect gastrointestinal motility

Neurologic disorders known to affect gastrointestinal motility. These disease processes involve craniosacral parasympathetic pathways (left), sympathetic pathways (middle), and/or primary enteric nerves or smooth muscle (right).

ENS: enteric nervous system; MNGIE: mitochondrial neurogastrointestinal encephalomyopathy.

Used with permission of American Society for Clinical Investigation, from: Camilleri M. Gastrointestinal motility disorders in neurologic disease. J Clin Invest 2021; 131:e143771. Copyright © 2021; permission conveyed through Copyright Clearance Center, Inc.

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