Recommended wait time for SOT candidates with a prior history of renal cell carcinoma

Stage	Recurrence-free survival 5 years (%)	Time interval to transplant
T1a (≤4 cm), N0, M0	95 to 98	No wait time
T1b (>4 cm to ≤7 cm), N0, M0	91 for FG 1/2	No wait time
T1b (>4 cm to ≤7 cm), N0, M0	80 to 82 for FG 3/4	1 to 2 years
T2 (7 to 10 cm), N0, M0	80	2 years
T3, N0, M0	43 to 80	Minimum of 2 years, then reassess
T4, N0, M0	28 to 55	Minimum of 2 years, then reassess
Any T, node positive, metastatic disease	0 to 32	Not a candidate (if solitary metastasis +resected, tumor board discussion on candidacy)
Any T with sarcomatoid and/or rhabdoid histologic features	15 to 27	Not a SOT candidate
Collecting duct or medullary RCC	<10	Not a SOT candidate

RCC: renal cell carcinoma; FG: Fuhrman grade (grade 1: inconspicuous nucleoli at ×400 magnification and basophilic, grade 2: clearly visible nucleoli at ×400 magnification and eosinophilic, grade 3: clearly visible nucleoli at ×100 magnification, grade 4: extreme pleomorphism or rhabdoid and/or sarcomatoid morphology).

From: Al-Adra DP, Hammel L, Roberts, J, et al. Pretransplant solid organ malignancy and organ transplant candidacy: A consensus expert opinion statement. Am J Transplant 2021; 21:460. https://onlinelibrary.wiley.com/doi/10.1111/ajt.16318. Copyright © 2021 John Wiley & Sons Ltd. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (https://onlinelibrary.wiley.com/).

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Recommended wait time for SOT candidates with a prior history of renal cell carcinoma