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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Recommended wait times pretransplantation for patients with a history of skin cancer before transplantation

Recommended wait times pretransplantation for patients with a history of skin cancer before transplantation
Skin malignancy Appropriate treatment pretransplantation Wait time before transplantation after treatment
cSCC
No history of SCC but at risk for development of SCC Treatment of field disease No delay necessary
Low risk Surgical excision with clear margins or Mohs micrographic surgery No delay necessary
High-risk SCC* (not including perineural invasion) Surgical excision with clear margins or Mohs micrographic surgery 2 years
High-risk SCC with:
  • Perineural invasion
  • or
  • ≥2 Risk factors
Surgical excision with clear margins or Mohs micrographic surgery ± ART 2 to 3 years
High risk with local nodal metastatic disease Surgical excision with appropriate lymph node dissection plus ART 5 years
Distant metastasis Refer for oncology opinion Not eligible for transplantation
MCC
Local with negative SLN biopsy Wide local excision ± ART 2 years
Local with nodal metastasis Wide local excision, lymph node dissection, ART 3 to 5 years
Distant metastasis Refer for oncology opinion Not eligible for transplantation
MM
In situ melanoma Wide local excision No wait necessary, follow-up posttransplantation 3 months
Stage Ia melanoma Wide local excision 2 years
Stage Ib/IIa melanoma Wide local excision ± sentinel lymph node biopsy 2 to 5 years
Stage IIb/IIc melanoma Wide local excision + sentinel lymph node biopsy 5 years
Any stage III or IV melanoma Refer for oncology opinion Not eligible for transplantation
ART: adjuvant radiation therapy; cSCC: cutaneous squamous cell carcinoma; MCC: Merkel cell carcinoma; MM: malignant melanoma; SCC: squamous cell carcinoma; SLN: sentinel lymph node biopsy.
From: Zwald F, Leitenberger J, Zeitouni N, et al. Recommendations for Solid Organ Transplantation for Transplant Candidates With a Pretransplant Diagnosis of Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma and Melanoma: A Consensus Opinion From the International Transplant Skin Cancer Collaborative (ITSCC). Am J Transplant 2016; 16:407. https://onlinelibrary.wiley.com/doi/10.1111/ajt.13593. Copyright © 2019 John Wiley & Sons Ltd. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (https://onlinelibrary.wiley.com/).
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