Risk category | Definition | Testing schedule |
High-risk, formula-fed infants: | Infants born to mothers with HIV who:
| Perform virologic testing with NAT at the following ages:
All infants at high risk of perinatal HIV transmission should have specimens obtained for HIV testing at birth before initiating an ARV drug regimen; however, presumptive HIV therapy should not be delayed |
Low-risk, formula-fed infants: | Infants born to mothers who:
| Perform virologic testing with NAT at the following ages:
|
Breastfed infants: | Infants who are breastfed by a mother with HIV | Perform virologic testing with NAT at the following ages:Δ
All breastfed infants should have specimens obtained for HIV testing at birth before initiating an ARV drug regimen; however, ARV prophylaxis should not be delayed |
ARV: antiretroviral; ART: antiretroviral therapy; NAT: nucleic acid test.
* For high-risk infants, virologic diagnostic testing is recommended at birth. For infants treated with multiple ARVs in the first 2 to 4 weeks of life, additional virologic testing is recommended 2 to 6 weeks after ARV drugs are discontinued (ie, at 8 to 12 weeks after birth).
¶ For low-risk infants, testing may be timed to occur at least 2 weeks after cessation of ARV prophylaxis.
Δ If the mother has a detectable viral load and continues breastfeeding, we prefer monthly virologic testing of the infant while the mother remains viremic.
◊ An additional virologic test should be performed at age 2 to 4 months if the gap between the tests at ages 1 to 2 months and 4 to 6 months is greater than 3 months.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟