Diagnostic criteria | Definition (any of the following) |
Significant bacteriuria | - ≥100,000 CFU/mL of a single uropathogen from a clean-catch specimen
- ≥50,000 CFU/mL of a single uropathogen from a catheterized specimen
- ≥1000 CFU/mL of uropathogenic bacteria from a suprapubic aspirate
|
Clinically relevant uropathogen* | - Escherichia coli
- Klebsiella spp
- Proteus spp
- Enterobacter spp
- Citrobacter spp
- Serratia marcescens
- Staphylococcus saprophyticus
- Enterococcus spp
- Streptococcus agalactiae
- Pseudomonas aeruginosa
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Symptomatic patient | Symptoms in infants and young children: |
Symptoms in older children: - Dysuria
- Frequency
- New-onset incontinence
- Abdominal pain
- Back pain
- Fever
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Pyuria (usually present)¶ | - Positive leukocyte esterase (≥trace) on dipstick analysis
- ≥5 WBC/high-power field on standardized microscopy
- ≥10 WBC/mm3 on a hemocytometer
- Pyuria according to automated microscopy
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