General approach to the pregnant patient with DIC caused by a pregnancy-related disorder (eg, abruption, amniotic fluid embolism, acute fatty liver of pregnancy, preeclampsia with severe features/HELLP syndrome)

DIC: disseminated intravascular coagulation; HELLP: syndrome of hemolysis, elevated liver enzymes, and low platelets.
* A provisional diagnosis of hemodynamic instability can be made in nonanesthetized pregnant patients with one or more of the following:

• Systolic blood pressure <100 mmHg
• Acute change in heart rate or systolic blood pressure by >15%
• Urine output <30 mL/hour
• Heart rate >100 beats per minute (NOTE: the 97^th percentile in normal pregnant people is approximately 115 beats per minute in the 3^rd trimester)

Other signs and symptoms of hemodynamic instability may be present, such as altered level of consciousness; shortness of breath; cold, clammy skin; and pallor.
¶ Refer to UpToDate content on management of abruption, amniotic fluid embolism, acute fatty lover of pregnancy, preeclampsia, and HELLP syndrome.
Δ Refer to UpToDate content on management of hemodynamically unstable pregnant patients with DIC.