Antithrombotic therapy according to cause of transient ischemic attack (TIA)

This algorithm is intended to provide basic guidance regarding the use of antithrombotic therapy based on mechanism for patients with a TIA. For further details, including suggested dosing regimens of antithrombotic agents, refer to the relevant UpToDate topic reviews.

ABCD²: age, blood pressure, clinical features, duration of symptoms, and diabetes; BP: blood pressure; CAS: carotid artery stenting; CEA: carotid endarterectomy; DAPT: dual antiplatelet therapy (eg, aspirin and clopidogrel, or aspirin and ticagrelor); DBP: diastolic blood pressure; ICA: internal carotid artery; SBP: systolic blood pressure.

* Indications for long-term oral anticoagulation include atrial fibrillation, ventricular thrombus, mechanical heart valve, and treatment of venous thromboembolism.

¶ Some experts prefer DAPT based upon observational evidence.

Δ Long-term single-agent antiplatelet therapy using aspirin, clopidogrel, or aspirin-extended-release dipyridamole.

Graphic 131695 Version 4.0

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Antithrombotic therapy according to cause of transient ischemic attack (TIA)