Plasma insulin responses to intravenous injections of glucose, isoproterenol, or arginine

The failure of beta cells in type 2 diabetes is relatively specific to glucose stimulation. Responses to other insulin secretagogues are relatively preserved.

IV: intravenous.

Data from:

Robertson RP, Porter Jr D. The glucose receptor. A defective mechanism in diabetes mellitus distinct from the beta adrenergic receptor. J Clin Invest 1973; 52:870.
Robertson RP, Bogachus LD, Oseid E, et al. Assessment of β-cell mass and α- and β-cell survival and function by arginine stimulation in human autologous islet recipients. Diabetes 2015; 64:565.

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