Acute insulin responses to intravenous glucose injections in people with varying fasting glucose levels

Reduction in insulin secretion in response to an intravenous glucose challenge at various levels of fasting glycemia. Even at relatively low fasting glucose values (100 to 114 mg/dL), the insulin secretion is demonstrably blunted.

IV: intravenous.

Reproduced from: Brunzell JD, Robertson RP, Lerner RL, et al. Relationships between fasting plasma glucose levels and insulin secretion during intravenous glucose tolerance tests. J Clin Endocrinol Metab 1976; 42(2):222-229. By permission of Oxford University press. Copyright © 1976.

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