ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
medimedia.ir

Anemia evaluation in outpatients (nonpregnant adults)

Anemia evaluation in outpatients (nonpregnant adults)
This algorithm addresses anemia in healthy outpatients, which is often an incidental finding or may be identified when a CBC is performed to evaluate mild symptoms such as fatigue. It is not appropriate for individuals who are acutely ill with fever, bleeding, neurologic symptoms, or any severe cytopenia (hemoglobin <7 to 8 g/dL; platelet count <50,000/microL, absolute neutrophil count [ANC] <1000/microL). Consider the history, CBC, MCV, and reticulocyte count (if available) simultaneously. Refer to UpToDate for details of testing for specific causes of anemia.
CBC: complete blood count; MCV: mean corpuscular volume; ACD/AI: anemia of chronic disease/anemia of inflammation; TSAT: transferrin saturation; MDS: myelodysplastic syndrome; RBC: red blood cell. 
* Iron studies include serum iron, transferrin, ferritin, and transferrin saturation (TSAT).
¶ Ferritin <30 ng/mL or TSAT <19% are generally used as evidence of iron deficiency. Ferritin is an acute phase reactant and may be higher in individuals with chronic inflammatory conditions.
Δ Other causes of anemia include monoclonal gammopathies, androgen deficiency (male), MDS, clonal cytopenias, copper deficiency, and others. Multiple causes may be present. The risks of clonal disorders and hematologic malignancies generally increases with age or exposure to bone marrow toxins including certain chemotherapy drugs. Aplastic anemia and Diamond-Blackfan anemia are less age dependent.
The reticulocyte count is helpful in narrowing the diagnosis of unexplained anemia. A high reticulocyte count typically indicates hemolysis; recovery from bleeding; removal of a bone marrow insult (drug or infection); or repletion of iron, folic acid, or vitamin B12. Genetic causes of hemolytic anemia may be associated with a positive family history and often have characteristic RBC morphologies on the blood smear that can be useful in guiding the evaluation.
Graphic 130710 Version 3.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟