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Pregnancy-related causes of DIC

Pregnancy-related causes of DIC
Abruptio placentae
Preeclampsia with severe features/eclampsia/HELLP syndrome
Amniotic fluid embolism
Acute fatty liver of pregnancy
Septic abortion
Severe PPH by itself usually does not cause DIC unless associated with increased release of tissue factor. Prolonged retention of a dead fetus over several weeks is now a rare cause of DIC because these cases are identified early and delivered without significant delay.
DIC: disseminated intravascular coagulation; HELLP: hemolysis, elevated liver enzymes, low platelets; PPH: postpartum hemorrhage.
Graphic 130588 Version 1.0

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