Population/clinical condition | Test (criteria for positive TST) | Rate of TB (per 1000 person-years) | Incidence rate ratio (Incidence Test Positive) (Incidence Test Negative) | ||
Estimate | 95% CI | Estimate | 95% CI | ||
General population (no TB risk factors) | TST (10 mm) | 0.3 | 0.1 to 1.1 | – | – |
Contacts | |||||
All contacts | IGRA | 13.3 | 10.8 to 16.4 | 8.4 | 5.2 to 13.5 |
TST (5 mm) | 8.4 | 4.3 to 16.5 | 12.5 | 6.4 to 22.5 | |
TST (10 mm) | 9.4 | 4.0 to 21.8 | 6.9 | 3.3 to 14.4 | |
Close contacts | IGRA | 22.4 | 12.1 to 41.8 | 13.1 | 3.3 to 51.9 |
TST (5 mm) | 10.5 | 7.7 to 14.3 | 3.7 | 2.1 to 6.5 | |
TST (10 mm) | 10.3 | 6.1 to 17.4 | 2.5 | 1.3 to 4.8 | |
Immunocompromised patients | |||||
HIV infection | IGRA | 16.9 | 10.5 to 27.3 | 11.0 | 4.6 to 26.2 |
TST (5 mm) | 27.1 | 15.0 to 49.0 | 11.1 | 6.2 to 19.9 | |
Dialysis | IGRA | 3.4 | 1.1 to 10.7 | 7.0 | 0.7 to 67.0 |
TST (5 mm) | 11.8 | 0.7 to 201.0 | 1.5 | 0.7 to 3.3 | |
TST (10 mm) | 100.8 | 42.1 to 243.0 | 2.6 | 1.4 to 4.8 | |
Transplant recipients | IGRA | 6.7 | 2.2 to 20.4 | 2.5 | 1.0 to 6.0 |
TST (5 mm) | 1.0 | 0 to 64.0 | 0.6 | 0.1 to 3.0 | |
TST (10 mm) | 3.7 | 0 to 862.0 | 2.4 | 0.9 to 6.4 | |
Other immunocompromising conditions | IGRA | 4.8 | 0.1 to 279.0 | 48.1 | 5.4 to 431.0 |
TST (5 mm) | 5.4 | 1.8 to 16.9 | 6.6 | 1.8 to 24.2 |
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