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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Scoring system for the diagnosis of DRESS

Scoring system for the diagnosis of DRESS
Clinical parameters Score Comments
–1 0 1
Fever ≥101.3°F (38.5°C) No/unknown Yes    
Lymphadenopathy   No/unknown Yes >1 cm, at least 2 sites
Eosinophilia ≥0.7 × 109 or ≥10% if leucopenia   No/unknown Yes Score 2 points of ≥1.5 × 109
Atypical lymphocytes   No/unknown Yes  
Skin rash
  • Rash suggestive of DRESS
 No Unknown Yes Suggestive features: ≥2 facial edemas, purpura, infiltration, desquamation
  • Extent ≥50% of BSA
   No/unknown Yes
Skin biopsy suggestive of DRESS No Yes/unknown    
Organ involvement   No Yes 1 point for each organ involvement, maximum score: 2
Disease duration ≥15 days No/unknown Yes    
Exclusion of other causes   No/unknown Yes 1 point if 3 of the following tests are performed and are negative: HAV, HBV, HCV, mycoplasma, chlamydia, ANA, blood culture
Total score:
  • <2: Excluded
  • 2 to 3: Possible
  • 4 to 5: Probable
  • ≥6: Definite
DRESS: drug reaction with eosinophilia and systemic symptoms; BSA: body surface area; HAV: hepatitis A virus; HBV: hepatitis B virus; HCV: hepatitis C virus; ANA: antinuclear antibody.
Adapted from:
  1. Kardaun SH, Sidoroff A, Valeyrie-Allanore L, et al. Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist? Br J Dermatol 2007; 156:609.
  2. Kardaun SH, Sekula P, Valeyrie-Allanore L, et al. Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study. Br J Dermatol 2013; 169:1071.
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