Causes of splenic abscess or infarction

Causes of splenic infarction

Cardioembolic

Malignant neoplasm

Hypercoagulable states other than cancer

Sickle cell disease

Trauma

Postoperative

Inflammatory (eg, pancreatitis)

Infectious (eg, sepsis, abscess, peritonitis)

Atherosclerosis

Cirrhosis

Causes of splenic abscess

Endocarditis

Pneumonia

Gastrointestinal perforation

Arteriovenous malformation

Common presenting findings include pain, fever, nausea or vomiting, and splenomegaly; some individuals may have leukocytosis and some may lack symptoms altogether (ie, an incidental finding). Refer to the source articles and UpToDate for information regarding the presentation, evaluation, and management of splenic infarction and splenic abscess.

Adapted from: Brett AS, Azizzadeh N, Miller EM, et al. Assessment of Clinical Conditions Associated With Splenic Infarction in Adult Patients. JAMA Intern Med 2020; 180:1125.

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Causes of splenic abscess or infarction