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تعداد ایتم قابل مشاهده باقیمانده : 4 مورد

Antibiotic regimens prior to uterine aspiration for pregnancy loss or termination

Antibiotic regimens prior to uterine aspiration for pregnancy loss or termination
When osmotic dilators* are NOT used:
  • Doxycycline 200 mg orally administered as a single dose within 60 minutes prior to uterine evacuation[1-3] or
  • Metronidazole 500 mg orally administered as a single dose within 60 minutes prior to uterine evacuation[1] or
  • Azithromycin 500 mg orally administered as a single dose within 60 minutes prior to uterine evacuation[1,3]
When osmotic dilators* are used:
  • Azithromycin 500 mg orally administered as a single dose at time of dilator placementΔ[1] or
  • Doxycycline 100 mg orally twice daily for 3 days; first dose given at time of dilator placement
For additional information, refer to the appropriate UpToDate clinical topics and Lexicomp drug information monographs included within UpToDate.
* Types of osmotic dilators include laminaria japonica and Dilapan-S.
¶ This is a commonly used regimen and is effective based on clinical experience but has not been well studied.
Δ Because of its long half-life, a second dose of azithromycin is only given if the surgical abortion is performed >24 hours after the initial dose of antibiotics.
References:
  1. Manual of medical standards and guidelines, Planned Parenthood Federation of America, Washington, DC 2016.
  2. American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Gynecology. ACOG Practice Bulletin No. 195: Prevention of Infection After Gynecologic Procedures. Obstet Gynecol 2018; 131:e172.
  3. Best practice in comprehensive abortion care. Royal College of Obstetricians and Gynaecologists. Available at: https://www.rcog.org.uk/globalassets/documents/guidelines/best-practice-papers/best-practice-paper-2.pdf (Accessed on July 22, 2020).
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