Antibiotic regimens prior to uterine aspiration for pregnancy loss or termination
|When osmotic dilators* are NOT used: |
- Doxycycline 200 mg orally administered as a single dose within 60 minutes prior to uterine evacuation[1-3] or
- Metronidazole 500 mg orally administered as a single dose within 60 minutes prior to uterine evacuation or
- Azithromycin 500 mg orally administered as a single dose within 60 minutes prior to uterine evacuation¶[1,3]
|When osmotic dilators* are used: |
- Azithromycin 500 mg orally administered as a single dose at time of dilator placementΔ or
- Doxycycline 100 mg orally twice daily for 3 days; first dose given at time of dilator placement¶
For additional information, refer to the appropriate UpToDate clinical topics and Lexicomp drug information monographs included within UpToDate.
- Manual of medical standards and guidelines, Planned Parenthood Federation of America, Washington, DC 2016.
- American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Gynecology. ACOG Practice Bulletin No. 195: Prevention of Infection After Gynecologic Procedures. Obstet Gynecol 2018; 131:e172.
- Best practice in comprehensive abortion care. Royal College of Obstetricians and Gynaecologists. Available at: https://www.rcog.org.uk/globalassets/documents/guidelines/best-practice-papers/best-practice-paper-2.pdf (Accessed on July 22, 2020).
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