Starting regimen for regional citrate anticoagulation with continuous venovenous hemodialysis

Patient weight (kg)	<60	60 to 90	>90
Blood flow (mL/minute)	80	100	120
Dialysate flow (mL/hour)	1500	2000	2500
4% Citrate (mL/hour)*	140	170	205
Calcium (mL/hour)^¶	38	50	65

* Citrate concentration is 136 mmol/L.

¶ Calcium concentration is 91 mmol/L.

From: Morgera S, Schneider M, Slowinski T, et al. A safe citrate anticoagulation protocol with variable treatment efficacy and excellent control of the acid-base status. Crit Care Med 2009; 37:2018. DOI: 10.1097/CCM.0b013e3181a00a92. Copyright © 2018 the Society of Critical Care Medicine. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.

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Starting regimen for regional citrate anticoagulation with continuous venovenous hemodialysis