The steps involved in clinical management of histologic HSIL

HSIL: high-grade squamous intraepithelial lesion; SCJ: squamocolumnar junction; CIN: cervical intraepithelial neoplasia; HPV: human papillomavirus; ASCCP: American Society for Colposcopy and Cervical Pathology; ECC: endocervical curettage.
* If CIN 2+ is identified at the margins of an excisional procedure or post-procedure ECC, colposcopy and ECC at 6 months or repeat excision are acceptable. Hysterectomy is recommended if re-excision is not feasible.
¶ Management options will vary in special circumstances or if the woman is pregnant or age <25 years. CIN 3 should always be treated, except in pregnancy. CIN 2 can be managed with observation if patients' concerns about pregnancy outweigh concerns about cancer.