This algorithm is only intended to provide guidance for individuals who have had genetic testing for HFE, the principal gene responsible for hereditary hemochromatosis (HH). It is not intended to imply that genetic screening is appropriate in the general population.
Refer to UpToDate for other aspects of the evaluation for suspected iron overload.
HFE: hereditary hemochromatosis gene.
* Generally includes testing for two variants, C282Y and H63D. Rarely, there may be a positive family history with a genetic cause other than HFE C282Y homozygosity or C282Y/H63D compound heterozygosity; in such cases it may be reasonable to test for the familial variant(s). If there is a family history of iron overload at a young age (<age 40 in men or in premenopausal women), it may be reasonable to test for other (non-HFE) hemochromatosis genes such as those discussed in UpToDate.
¶ Other reasons to perform iron studies include:آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟