The figure shows locations of the localization of causative mutations in the fibrinogen-encoding genes FGA, FGB, and FGG (adapted from the UCSC Genome Browser PDF view of the fibrinogen cluster). Numbers under each exon indicate the total number of mutated alleles identified/the number of mutated alleles leading to afibrinogenemia and hypofibrinogenemia/the number of mutated alleles leading to dysfibrinogenemia and hypodysfibrinogenemia. Exons of particular importance for screening of congenital fibrinogen disorders are encompassed by the dashed red lines.
