ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
medimedia.ir

Current proposed PET radiopharmaceuticals for PPGL imaging according to genetic background

Current proposed PET radiopharmaceuticals for PPGL imaging according to genetic background
  Location Other related tumor conditions First-choice radiopharmaceutical Second-choice radiopharmaceutical
SDHB Adrenal/extra-adrenal GISTs, RCCs, and pituitary adenomas 68Ga-DOTA-SSAs 18F-FDG
SDHD Adrenal/extra-adrenal GISTs, RCCs, and pituitary adenomas 68Ga-DOTA-SSAs 18F-FDG
SDHC Adrenal/extra-adrenal GISTs and RCCs 68Ga-DOTA-SSAs 18F-FDG
FH Adrenal/extra-adrenal Skin and uterine leiomyomas, RCCs, uterine leiomyosarcomas, and ovarian mucinous cystadenomas 18F-FDOPA 68Ga-DOTA-SSAs
VHL Adrenal/extra-adrenal RCCs, CNS hemangioblastomas, and pancreatic and testicular tumors 18F-FDOPA 68Ga-DOTA-SSAs
EPAS1/HIF2A Adrenal/extra-adrenal Somatostatinomas 18F-FDOPA 18F-FDG
MEN2 Adrenal MTC, parathyroid adenomas, or hyperplasia 18F-FDOPA 68Ga-DOTA-SSAs
NF1 Adrenal Neurofibromas, peripheral nerve sheath tumors, and gliomas 18F-FDOPA 68Ga-DOTA-SSAs
TMEM127 Adrenal RCCs 18F-FDOPA 68Ga-DOTA-SSAs
MAX Adrenal/extra-adrenal Renal oncocytomas 18F-FDOPA 68Ga-DOTA-SSAs
PET: positron emission tomography; PPGL: pheochromocytoma and paraganglioma; SDH: succinate dehydrogenase; GIST: gastrointestinal stromal tumor; RCC: renal cell carcinoma; 68Ga-DOTA: gallium Ga-68 DOTA; SSA: somatostatin analog; 18F-FDG: 18F-fludeoxyglucose; FH: fumarase hydratase; 18F-FDOPA: 18F-fluorodihydroxyphenylalanine; VHL: von Hippel-Lindau tumor suppressor; CNS: central nervous system; EPAS1: endothelial PAS domain-containing protein 1; HIF2A: hypoxia-inducible factor 2-alpha; MEN2: multiple endocrine neoplasia 2; MTC: medullary carcinoma of the thyroid; NF1: neurofibromatosis type 1 protein; TMEM127: transmembrane protein 127; MAX: MYC-associated factor X.
Reproduced from: Taïeb D, Pacak K. New Insights into the Nuclear Imaging Phenotypes of Cluster 1 Pheochromocytoma and Paraganglioma. Trends Endocrinol Metab 2017; 28:807. Table used with the permission of Elsevier Inc. All rights reserved.
Graphic 122805 Version 1.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟