Electron microscope images of structural changes in diabetic kidney disease

(A) Structural changes in diabetic glomerulopathy found with electron microscopy. C indicates marked expansion of the mesangium. D indicates marked diffuse thickening of capillary basement membranes (to 3 times the normal thickness in this case). E indicates segmental effacement of the visceral epithelial foot processes. Original magnification, ×3500.
(B) Normal glomerulus.