Approach to fertility preservation for patients undergoing gonadotoxic therapy*

* For detailed discussions of fertility preservation techniques and their application, refer to UpToDate content on ovulation induction, in vitro fertilization, and fertility preservation.

¶ Testicular cryopreservation is under investigation and not yet routinely available.

Δ In most patients, random-start protocols allow ovarian stimulation to be initiated at any time without needing to wait for menses.

◊ Choice of agent for ovarian stimulation is impacted by the type of tumor, estrogen receptor status, and presence of BRCA gene mutations.