Radiograph, magnetic resonance imaging, and bone scan of a patient with localized osteosarcoma of the right distal femur

(A) Radiograph showing a destructive sclerotic lesion in the medial aspect of the right distal femur with an associated aggressive periosteal reaction, including a Codman triangle (arrow).
(B) Postcontrast T1 fat-saturated coronal MRI of the tumor showing both an intraosseous and extraosseous component.
(C) Total body radionuclide bone scanning with technetium showing prominent focal radiotracer uptake at the site of the primary tumor (thick arrow) in the right distal femur and no distant areas of abnormal increased radiotracer uptake.