TTP: thrombotic thrombocytopenic purpura; TPE: therapeutic plasma exchange; CBC: complete blood count; LDH: lactate dehydrogenase.
* Defined as a platelet count ≥150,000/microL for at least 2 days or a stable platelet count plateau in the normal or supranormal range for 3 days. Refer to UpToDate for details.
¶ Daily assessment of clinical status, CBC, and LDH is done for approximately 2 to 3 days after stopping TPE; monitoring is then extended slowly, with the exact timing dependent on clinical status.
Δ Individuals who have a recurrence within a month of the acute episode are considered to have refractory disease and are treated more aggressively. Those who have a recurrence >1 month after the acute episode are considered to have a relapse and are treated for a new episode, similarly to the previous episode. Refer to the UpToDate algorithm on initial treatment of TTP and the UpToDate topic on treatment of refractory or relapsed TTP for details of management.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟