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Possible symptoms of autism spectrum disorder in preschool-aged children (age 3 to 5 years)

Possible symptoms of autism spectrum disorder in preschool-aged children (age 3 to 5 years)
Impairments in social communication and interaction
Impaired verbal and nonverbal communication
  • Lack of, delay, or regression in spoken language.
  • Spoken language, if present, may be atypical. For example:
    • Unusual intonations (monotone, sing-song).
    • Echolalia.
    • Incorrect pronoun use (referring to self by name or as "you," "he," or "she" after age 3 years).
    • Non-speech-like vocalizations (eg, grunting, squealing).
    • Limited to specific topics of interest.
  • Limited use of language for communication (eg, using only single words even though capable of speaking in sentences).
  • Lack of response or slow to respond when called by name (despite normal hearing).
  • Reduced or absent nonverbal communication (eg, gestures, facial expression).
Impaired social-emotional reciprocity and inability to establish peer friendships
  • Little or no response to others' gestures or facial expressions.
  • Reduced or absent interest in or attempts to share interest with another person (eg, by pointing or monitoring the other's gaze). For example:
    • Lack of social smile or eye contact.
    • Lack of imitation (eg, clapping).
    • Limited or absent social bids.
    • Lack of ability or interest in sustaining a social interaction.
    • Resistance to being cuddled.
  • Lack of awareness of other people; appearing to focus inward or "be in their own world."
  • Preference for solitary play (lack of initiation or participation in social play with others).
  • Lack of interest in other children or odd social approaches to other children (eg, disruptive, aggressive).
  • Lack of awareness of common social conventions (eg, taking turns in a conversation, awareness of personal space).
  • Lack of or minimal recognition or responsiveness to another's feelings (eg, happiness, distress).
  • Other atypical interactions with peers or adults. For example:
    • Normal or even exaggerated level of motivation to socialize, with limited ability to infer the intentions or behaviors of others.
    • Unable to sustain mutually enjoyable social interactions due to an inability to respect social conventions (eg, personal boundaries) or to anticipate the knowledge and interests of others (eg, may talk only about preferred interests and not engage in the social partner's interests).
Repetitive behaviors/restricted interests and atypical sensory reactions*
  • Repetitive/stereotyped motor and vocal mannerisms (eg, hand flapping, rocking behaviors, echolalia).
  • Resistance to change, insistence on following the same routines.
  • Re-enacting or repeating scenes or scripts that have been heard (eg, from videos or cartoons).
  • Atypical play:
    • Repetitive (eg, lines up objects, opens and closes doors, turns lights on and off).
    • Lacking imaginative/creative play.
    • No pretend play (eg, feeding doll).
    • Over-attention to parts of objects (eg, spinning wheels).
  • Lack of or unusual reaction to sensory stimuli (eg, noise, texture, smells).
This table is intended for use in conjunction with UpToDate content on autism spectrum disorder (ASD). The list of symptoms is not all-inclusive. It is meant to prompt clinicians to consider the possibility of ASD. Additional criteria and comprehensive evaluation are necessary for diagnosis. Refer to UpToDate content on ASD in children and adolescents for details.
* Repetitive behaviors and sensory sensitivities are developmentally expected reactions in preschool-aged children. The behaviors outlined here should be persistent, pervasive, and/or interfere with daily routines before they are considered to be atypical.
References:
  1. Hyman SL, Levy SE, Myers SM, Council on Children with Disabilities, Section on Developmental and Behavioral Pediatrics. Identification, evaluation, and management of children with autism spectrum disorder. Pediatrics 2020; 145.
  2. Whaikaha – Ministry of Disabled People and the Ministry of Education: Aotearoa New Zealand autism guideline, 3rd edition. 2022. Available at: https://www.health.govt.nz/publication/new-zealand-autism-spectrum-disorder-guideline (Accessed on November 5, 2024).
  3. Scottish Intercollegiate Guidelines Network (SIGN). Assessment, diagnosis and interventions for autism spectrum disorders. SIGN 145. June 2016. Available at: https://www.sign.ac.uk/assets/sign145.pdf (Accessed on November 5, 2024).
  4. National Institute for Health and Care Excellence. Autism spectrum disorder in under 19s: Recognition, referral, and diagnosis. September 2011 (Updated 2017). Available at: https://www.nice.org.uk/guidance/cg128 (Accessed on November 5, 2024).
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