Systemic rheumatic diseases difficult to exclude in patients presenting primarily with widespread pain and fatigue

Rheumatic disease	Helpful differential diagnostic features
SLE	Rash, systemic signs/symptoms, elevated ESR/CRP Significantly positive ANA, anti-DNA antibody Abnormal hematologic tests
PMR	Proximal muscle stiffness rather than pain Age greater than 60 Elevated ESR/CRP
Spondyloarthritis	Primarily back pain and stiffness Limited spine mobility Elevated ESR/CRP Abnormal radiographs/imaging
Myopathy/myositis	Muscle weakness Elevated CK

SLE: systemic lupus erythematosus; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; ANA: antinuclear antibodies; PMR: polymyalgia rheumatica; CK: creatine kinase.

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خرید پکیج

Systemic rheumatic diseases difficult to exclude in patients presenting primarily with widespread pain and fatigue