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NCI CTCAE v5.0 capillary leak syndrome

NCI CTCAE v5.0 capillary leak syndrome
Adverse event Grade 1 Grade 2 Grade 3 Grade 4 Grade 5
Capillary leak syndrome Asymptomatic Symptomatic; medical intervention indicated Severe symptoms; intervention indicated Life-threatening consequences; urgent intervention indicated Death
Capillary leak syndrome is characterized by leakage of intravascular fluids into the extravascular space. This syndrome is observed in patients who demonstrate a state of generalized leaky capillaries following shock syndromes, low-flow states, ischemia-reperfusion injuries, toxemias, medications, or poisoning. It can lead to generalized edema and multiple organ failure.
NCI CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events.
Reproduced from: Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0, November 2017, National Institutes of Health, National Cancer Institute. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/CTCAE_v5_Quick_Reference_8.5x11.pdf (Accessed September 21, 2018).
Graphic 119056 Version 2.0

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