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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Classical immunophenotype of lower grade lymphoproliferative disorders

Classical immunophenotype of lower grade lymphoproliferative disorders
  CD5 CD19 CD20 CD23 CD10 CD25 CD103 CD200 sIg
CLL + + Dim + +/– + Dim
MCL + + Bright –/Dim +/– Bright
FL + + +/– + +
MZL –/+ + Bright –/+ +/– +/Bright
HCL Bright Bright + + + +
HCL variant Bright Bright + +
WM/LPL –/+ + + +/– –/+ +/– + +/Variable
B-PLL + Bright –/+ –/+ Bright
The order of descriptors reflects the predominant expression pattern (ie, +/– implies that most cases express the antigen). "Bright" and "Dim" refer to expression levels relative to that of normal B lymphocytes.
CD: cluster of differentiation; sIg: surface immunoglobulin; CLL: chronic lymphocytic leukemia; MCL: mantle cell lymphoma; FL: follicular lymphoma; MZL: marginal zone lymphoma; HCL: hairy cell leukemia; WM: Waldenström macroglobulinemia; LPL: lymphoplasmacytic lymphoma; B-PLL: B cell prolymphocytic leukemia.
References:
  1. Fujiwara S, Tatara R, Okazuka K, et al. Profiles Of De Novo CD25-Positive Mature B-Cell Lymphomas. Blood 2013; 122:4308.
  2. Sandes AF, de Lourdes Chauffaille M, Oliveira CR, et al. CD200 has an important role in the differential diagnosis of mature B-cell neoplasms by multiparameter flow cytometry. Cytometry B Clin Cytom 2014; 86:98.
  3. Mason EF, Pozdnyakova O, Li B, et al. Flow Cytometric Patterns of CD200 and CD1d Expression Distinguish CD10-Negative, CD5-Negative Mature B-Cell Lymphoproliferative Disorders. Am J Clin Pathol 2017; 148:33.
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