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Patients for whom consensus supports use of HF-WBI: A comparison of the 2011 and 2018 ASTRO guidelines

Patients for whom consensus supports use of HF-WBI: A comparison of the 2011 and 2018 ASTRO guidelines
Factor 2011 Guideline 2018 Guideline
Age ≥50 years Any
Stage T1-2 N0 Any stage provided intent is to treat the whole breast without an additional field to cover the regional lymph nodes
Chemotherapy None Any chemotherapy
Dose homogeneity ±7% in the central axis Volume of breast tissue receiving >105% of the prescription dose should be minimized regardless of dose-fractionation
These guidelines are intended as a tool to promote appropriately individualized, shared decision-making between physicians and patients. None should be construed as strict or superseding the appropriately informed and considered judgments of individual physicians and patients; therefore, the task force recommends against any quality benchmarks requiring 100% utilization of HF-WBI, even in patients where recommendations for HF-WBI are strong because the distribution of reasonable patient values and preferences would be expected to yield a patient-centered choice for conventionally fractionated WBI in a certain proportion of individual patients.
ASTRO: American Society for Radiation Oncology; HF-WBI: hypofractionated whole-breast radiation.
Reproduced from: Smith BD, Bellon JR, Blitzblau R, et al. Radiation therapy for the whole breast: Executive summary of an American Society for Radiation Oncology (ASTRO) evidence-based guideline. Pract Radiat Oncol 2018; 8:145. Table used with the permission of Elsevier Inc. All rights reserved.
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