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Oral bicarbonate and bicarbonate equivalent salts used for systemic and/or urinary alkalinization

Oral bicarbonate and bicarbonate equivalent salts used for systemic and/or urinary alkalinization
Generic name Common brand names (US) and form Electrolyte and bicarbonate content*
Potassium citrate Urocit-K (tablet, controlled release) Tablet: Each pill contains 5, 10, or 15 mEq potassium and delivers the equivalent of 5, 10, or 15 mEq bicarbonate.
Potassium citrate-citric acid Polycitra K, Cytra-K (powder or solution)

Powder: Each packet contains 30 mEq potassium and delivers the equivalent of 30 mEq of bicarbonate.

Solution: Each 5 mL contains 10 mEq potassium and delivers the equivalent of 10 mEq bicarbonate.
Sodium citrate-citric acid Bicitra, Cytra-2, Oracit, Shohl's solution modified (solution) Solution: Each 5 mL contains 5 mEq sodium and delivers the equivalent of 5 mEq bicarbonate.
Sodium citrate-potassium citrate-citric acid Polycitra, Cytra-3 (solution, syrup) Solution (syrup): Each 5 mL contains 5 mEq potassium and 5 mEq sodium and delivers equivalent of 10 mEq bicarbonate.
Potassium bicarbonate-potassium citrate Klor-Con/EF, Effer-K, K-Effervescent (effervescent tablet) Effervescent tablet (diluted in water): Each tablet contains 10, 20, or 25 mEq potassium and delivers approximately 10, 20 or 25 mEq bicarbonate or equivalent.
Sodium bicarbonate Tablet Tablet: Each 650 mg tablet contains 7.7 mEq of sodium and 7.7 mEq of bicarbonate (325 mg tablet contains 3.8 mEq of bicarbonate).
Baking soda (powder) Powder: One-half teaspoonful (2.4 grams) contains approximately 29 mEq of sodium and 29 mEq bicarbonate (roughly equivalent to three 650 mg sodium bicarbonate tablets).[1]
For approach to product selection, dosing recommendations, and target urine pH for alkalinization therapy, refer to separate UpToDate clinical reviews of uric acid nephrolithiasis and cystine stones.
* Orally administered citrate is a bicarbonate equivalent.
Reference:
  1. Al-Abri SA, Kearney T. Baking soda misuse as a home remedy: case experience of the California Poison Control System. J Clin Pharm Ther 2014; 39:73.
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