ﺑﺎﺯﮔﺸﺖ ﺑﻪ ﺻﻔﺤﻪ ﻗﺒﻠﯽ
خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
medimedia.ir

Examples of mutations of the DMD gene

Examples of mutations of the DMD gene
Examples of mutations of the DMD gene and their consequences on the production of dystrophin and the corresponding phenotypes. The boxes represent exons. Right faces of boxes indicate that the exon codes for an entire protein sequence based on three-bases codons (examples: exons 47, 48, 49). Curved faces indicate that the exon does not code for an entire protein sequence but that either the first or the last bases need the preceding or following exon to code a full three-bases codon (examples: exons 50, 51, 52).
BMD: Becker muscular dystrophy; DMD: Duchenne muscular dystrophy.
* Missense mutations may sometimes cause DMD.
¶ Nonsense mutations may sometimes cause BMD.
From: Le Rumeur E. Dystrophin and the two related genetic diseases, Duchenne and Becker muscular dystrophies. Bosn J Basic Med Sci 2015; 15:14. Available at: http://www.bjbms.org/ojs/index.php/bjbms/article/view/636. Reproduced under the terms of the Creative Commons License 4.0.
Graphic 117464 Version 2.0

آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟