Collection tube and high- and low-power views of the blood smear in a patient with Mycoplasma-associated cold agglutinin syndrome
An 18 year old with sickle cell disease and an acute febrile illness had discrepant ABO blood typing (front-typed as AB, back-typed as O) due to a cold autoantibody, which led to the diagnosis of Mycoplasma pneumoniae infection. Cold agglutinins caused red blood cell agglutination, which was visible in the anticoagulated blood sample tube and on low-power (20X) and high-power (100X) views of the peripheral blood smear (panels A, B, and C, respectively). The cold agglutinin titer was 512.
From: Nixon CP, Sweeney JD. Facilitation of the clinical diagnosis of Mycoplasma pneumoniae by the blood bank. Transfusion 2017; 57:2564.
http://onlinelibrary.wiley.com/wol1/doi/10.1111/trf.14115/abstract. Copyright © 2017 AABB. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email:
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