PLA2R staining versus anti-PLA2R versus proteinuria schematic

Schematic representation of the temporal association of serological tests for anti-PLA2R, tissue staining for PLA2R, and clinical activity represented by proteinuria. Note that tissue staining for PLA2R may precede the appearance of circulating anti-PLA2R and persist after the antibodies disappear from circulation. Resolution of proteinuria lags behind immunological remission.