Antiviral treatment for chronic hepatitis E virus in treatment-naïve nonpregnant adults

HEV: hepatitis E virus.
* In solid organ transplant recipients, we typically reduce tacrolimus first if possible. In addition, for such patients, we administer antiviral therapy in conjunction with reducing immunosuppressive therapy.
¶ HEV RNA assay should be performed in both stool and serum.
Δ HEV RNA should not detected in both stool and serum.
◊ HEV RNA detected in either stool or serum.