Version May 2024
| Clinical variable | Lower risk | High risk |
| Clinical evidence of RV failure | No | Yes |
| Progressive symptoms | No | Yes |
| WHO functional class | I to II | III to IV |
| Growth | Normal | Poor weight gain and/or growth failure |
| Syncope | None | Recurrent |
| BNP/NT-proBNP | Minimally elevated | Markedly elevated and/or rising |
| 6MWD (for children >6 years old) | ≥350 meters | <350 meters |
| Echocardiography | Minimal RV enlargement and/or dysfunction | Considerable RA/RV enlargement Reduced LV size Increased RV/LV ratio Reduced TAPSE Low RV FAC Pericardial effusion |
| Hemodynamics measured by cardiac catheterization | Systemic CI >3.0 L/min/m2 Systemic venous saturation >65% Reactive AVT | Systemic CI <2.5 L/min/m2 mRAP >10 mmHg PVRI >20 WU•m2 Systemic venous saturation <60% PACI <0.85 mL/mmHg/m2 |
This stable summarizes the approach to severity assessment in children with PH based upon the clinical criteria listed above. Categorization as lower versus high risk is not precise and is based in part on the clinical judgment of the treating clinician. For the lower-risk category, all standard criteria should generally be met; for the high-risk category, patients typically meet multiple criteria, though all criteria need not be met. Some patients have intermediate findings and do not fall clearly into a lower- or high-risk category.
This table is intended for use in conjunction with additional UpToDate content on PH in children. Refer to UpToDate topics on the evaluation and management of PH in children for additional details.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
