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Clinical features and epidemiologic associations with selected pathogens that can cause prolonged cough

Clinical features and epidemiologic associations with selected pathogens that can cause prolonged cough
Pathogen* Clinical features and epidemiologic associations
Influenza virus Acute onset fever, chills, myalgias, and cough during influenza season or in patients with known exposure or recent travel.
Bordetella pertussis Cough lasting ≥2 weeks without an apparent cause, with one of the following symptoms: paroxysms of coughing, inspiratory whoop, or post-tussive emesis, particularly during outbreaks or in patients with known exposures.
Bordetella bronchiseptica Pertussis-like syndrome in a patient with animal exposure, particularly if immunocompromised.
Mycoplasma pneumoniae No distinguishing clinical features, although outbreaks reported across large geographic regions and among families or persons living in close quarters.
Chlamydia pneumoniae No distinguishing clinical features, although outbreaks reported in persons living in close quarters.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Common features include cough, myalgias, headache, and sore throat. Smell and taste abnormalities were associated with certain viral variants circulating early in the pandemic.
* There is a wide range of clinical features associated with each pathogen. For a comprehensive review, refer to the UpToDate content on each pathogen.
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