Heath and Edwards pathological classification of pulmonary artery hypertension
Heath and Edwards pathological classification of pulmonary artery hypertension
Panels A and C are from a 38-year-old woman with severe PAH associated with systemic sclerosis. Panels B and D are from a 40-year-old woman with a ventricular septal defect and Eisenmenger syndrome. (A) Grade II lesion depicting intimal hyperplasia and medial hypertrophy. (B) Grade III lesion depicting an "onion-skin" appearance and vessel occlusion. (C) Grade IV depicting a plexiform lesion (asterisk). (D) Grade VI lesion depicting a plexiform lesion with fibrinoid necrosis.
PAH: pulmonary artery hypertension.
Graphic 114113 Version 2.0
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